Cisplatin pulmonary toxicity
WebDec 7, 2024 · Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive disease with poor survival, and platinum-etoposide chemotherapy is indicated as the mainstay of … Webprimary pulmonary toxicity of cisplatin in cats. (Journal of Veterinary Internal Medicine. 1987; 129-35) CISPLATIN (cis-diamminedichloroplatinum) is a widely used …
Cisplatin pulmonary toxicity
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WebJan 12, 2024 · Cisplatin has severe nonhematological toxicities, particularly nephrotoxicity and gastrointestinal toxicity. The recent development of new antiemetic therapies has greatly reduced... WebSep 4, 2013 · The short hydration is safe without severe renal toxicities in regimens containing cisplatin (≥75 mg/m 2) for patients with lung cancer. short hydration, magnesium supplementation, cisplatin, lung cancer, renal toxicity Topic: chemotherapy regimen cisplatin creatinine kidney failure mannitol safety kidney lung cancer pemetrexed toxic …
WebClinical Comparative Investigation of Efficacy and Toxicity of Cisplatin plus Clinical comparative investigation of efficacy and toxicity of cisplatin plus gemcitabine or plus Abraxane as first-line chemotherapy for stage III/IV non-small-cell lung cancer Dan Ai,1,2 Yan Guan,2 Xiu-Ju Liu,2 Chu-Feng Zhang,1,2 Peng Wang,1,2 Hong-Lu Liang,1,2 Qi … WebFeb 2, 2024 · Cisplatin can cause not only nephrotoxicity but also cause severe neurotoxicity, which significantly limits its clinical use. A study showed that a continuous high dose of cisplatin stimulation disrupted the blood-brain barrier, leading to brain cell edema and neuronal necrosis (Namikawa et al., 2000). Regarding the study of prevention and ...
WebApr 26, 2024 · To assess the prognostic impact of BPT, we retrospectively identified 52 patients who underwent bleomycin etoposide and cisplatin chemotherapy from 2008 to 2024 in our institution, and evaluated the risk factors of BPT and its effect on prognosis. Patients who had received chemotherapy at another institution were excluded. WebOct 7, 2024 · Depending on a dose (single or cumulative) cisplatin can cause leucocytopenia, thrombocytopenia, and anemia also in mice (toxicity on hemopoietic cells, Figure 1 ). Myelotoxicity can be observed already a day after cisplatin administration and is more toxic for earlier hemopoietic progenitor cells than for the mature cells [ 74 ].
WebIn group 1, cisplatin was administered at a dose of 60 mg/m2 to four cats. In an attempt to avoid renal toxicity, saline diuresis was induced by administering 0.9% saline solution …
WebCancer immunotherapy significantly contributed to an improvement in the prognosis of cancer patients. Immunotherapy, including human epidermal growth factor receptor 2 (HER2)-targeted therapies, immune checkpoint inhibitors (ICI), and chimeric antigen receptor-modified T (CAR-T), share the characteristic to exploit the capabilities of the … impediment bathroomWebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the … impediment and blockerWebAug 1, 1998 · Cisplatin doses were fixed and were not reduced for any toxicity. The most common reasons for irinotecan dose reduction were nausea and vomiting (27% of patients), followed by diarrhea (21%), and neutropenia (12%). Response and Survival All patients were evaluated for response and survival. impediment breakerWebBased on 4448 patients, the incidences of dyspnea and other serious pulmonary toxicity were 0.45% and 0.27% respectively. Based on an estimated 217 400 patients treated with commercial gemcitabine worldwide, the crude incidences of dyspnea and other serious pulmonary toxicity were 0.02% and 0.06% respectively. impediment etymologyWebSep 15, 2024 · Common side effects include nausea, vomiting, bone marrow suppression, electrolyte imbalance, neuropathy, ototoxicity and nephrotoxicity. Cisplatin is mutagenic, … impediment boardWebMar 29, 2015 · Cisplatin-based regimens are associated with enhanced efficacy and toxicity as compared with carboplatin-based therapy 32,33; yet in CALGB protocol 9633, 27 33 percent of patients required dose... impediment crossword clue 9 lettersWebIntroduction: The aim of this multicenter phase II trial was to evaluate the combination of oral vinorelbine and cisplatin with radiotherapy (RT) after cisplatin-docetaxel induction chemotherapy (CT) in patients with locally advanced non-small cell lung cancer (NSCLC). Patients and methods: Patients with previously untreated, inoperable, histologically or … lisw stands for