Kif18a cancer
Web3 mei 2024 · Conclusions: The identification of KIF18A as a new biomarker for glioma could help elucidate how changes in the glioma cell and immune microenvironment promote … Web28 mrt. 2015 · Kif18A, the kinesin-8 motor protein, plays an essential role in regulating alignment of bi-oriented chromosomes at the midzone during mitosis. Kinesin proteins, …
Kif18a cancer
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Web16 jun. 2024 · Liu, X.-S. et al. Germinal cell aplasia in Kif18a mutant male mice due to impaired chromosome congression and dysregulated BubR1 and CENP-E. Genes Cancer 1, 26–39 (2010). Article CAS Google Scholar Web1 nov. 2024 · KIF18A is a kinesin family member that is involved in various cellular processes including cell division, cell transformation, and carcinogenesis. However, its possible role in the regulation of host immunity has not been examined. Objective
WebKIF18A, a member of kinesin-8 family, plays pivotal roles in regulating microtubule dynamics, chromosome con-gression and cell division [3 ]. KIF18A is involved in several cancers: breast, colorectal and hepatocellular cancers and cholangiocarcinoma [4 –7] particularly driving proliferation, migration and anoikis in BC [4 ]. WebExpression of KIF18A (DKFZP434G2226, PPP1R99) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to …
WebKinase-like protein 18A (KIF18A) is a mitotic kinesin motor protein that regulates chromosome positioning during cell division and is overexpressed in a subset of human … WebLUNG CANCER NON-SMALL CELL LUNG CANCER (continued) 5 05052801 Amgen ID*: 20240096 Status 3 A Phase 3 Study of Bemarituzumab or Placebo Plus Chemotherapy in ... Small molecule targeting KIF18A being evaluated in advanced solid tumors NCT: 04293094 Amgen ID*: 20240131 Status Phase 1
WebALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; KIF18A, kinase-like protein 18A; KRAS, Kirsten rat sarcoma; MCL-1, myeloid cell leukemia-1; MM, multiple myeloma; NSCLC, non-small cell lung cancer. References 1. 2. 3. Handb Exp Pharmacol. 2014;219:1-12. 4. J Cereb Blood Flow Metab. 2012;32:1959-1972. 5. 6. 7. 8. 9. 10. 11. …
Web22 mrt. 2024 · March 22, 2024. Volastra Therapeutics Inc. has divulged kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer. BioWorld Science … historia 2 bachillerato bloquesWeb15 apr. 2024 · KIF18A, KIF15 and KIF4A were demonstrated prognostic biomarkers for prediction of clinical outcomes [20, 70]. Furthermore, expression of KIF18A was … homewood suites raleigh crabtree valleyWeb10 okt. 2024 · KIF18A, a member of kinesin-8 family, plays pivotal roles in regulating microtubule dynamics, chromosome congression and cell division [ 3 ]. KIF18A is … historia2.seWeb8 feb. 2024 · Prognostic Analysis of KIF18A. The clinical information of 33 tumors was downloaded from the TCGA database. We selected overall survival (OS), disease … historia 2020 maturaWeb7 mrt. 2024 · NEW YORK, March 7, 2024 – Volastra Therapeutics, a clinical stage cancer biotechnology company focused on exploiting chromosomal instability (CIN), today … historia 2 bachillerato evauWebBackground: KIF18A is a kinesin assisting chromosome congression and alignment during mitosis. It is nonessential in normal, euploid cell division but essential for a subset of aneuploid cancer cells with high chromosomal instability (CIN-high). KIF18A knockdown in these cells leads to mitotic arrest, cy-tostasis and cell death. homewood suites redondo beach reviewsWeb11 jun. 2024 · Kinesin family member 18A (KIF18A) is significantly overexpressed and is related to the poor prognosis of human cancers. However, the function of KIF18A in … homewood suites redondo beach